UTSA vs. South Florida odds, line: 2025 college football picks for Week 11 predictions from proven model - SportsLine.com

UTSA vs. South Florida Odds and Predictions for Week 11

The South Florida Bulls aim to stay competitive in the American Athletic Conference championship race as they face the UTSA Roadrunners in a crucial Thursday night game.

Team Records and Recent Games

Scoring Trends

Game Details and Odds

Kickoff is scheduled for 7:30 p.m. at Raymond James Stadium in Tampa, Florida.

UTSA won the only previous meeting between the teams with a 49-21 triumph in 2023.

The Bulls enter as 14-point favorites. The over/under for total points is set at 67.5 by SportsLine consensus.

Team Money Line Betting Odds
South Florida -610 Risk $610 to win $100
UTSA +445 Risk $100 to win $445

Expert Analysis

"South Florida picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model. The model simulates every FBS game 10,000 times."

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Author’s summary: South Florida hosts a key matchup against UTSA, backed by strong home performance and expert betting models forecasting a high-scoring contest with the Bulls favored.

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SportsLine SportsLine — 2025-11-06