Familial Clustering in Primary Hyperparathyroidism
Research has identified familial clustering in primary hyperparathyroidism, indicating that first-degree relatives of patients are at a higher risk of developing the condition.
A study published in the Journal of the Endocrine Society found that first-degree relatives of patients with primary hyperparathyroidism are more likely to have the condition themselves. However, the link between primary hyperparathyroidism and cancer risk among family members is less clear.
Prior studies have suggested a connection between primary hyperparathyroidism and an increased risk of malignancy, with a recent meta-analysis showing a pooled prevalence of 20% for any type of cancer among this population.
First-degree relatives of patients with primary hyperparathyroidism are at greater risk of having the condition themselves, but a link to cancer risk among parents, siblings, and children is less certain.
- First-degree relatives are at higher risk of primary hyperparathyroidism.
- The link between primary hyperparathyroidism and cancer risk is uncertain.
Author's summary: Familial clustering is identified in primary hyperparathyroidism.