Brekiya Now Available for Migraine, Cluster Headache Treatment

Introducing Brekiya for Migraine and Cluster Headache Treatment

Brekiya® is now available for the acute treatment of migraine with or without aura and cluster headaches in adults.

Brekiya is a ready-to-use dihydroergotamine (DHE) autoinjector, supplied as a 1mL prefilled single-dose autoinjector containing 1mg/mL of DHE.

In patients with migraine, the therapeutic activity of DHE is generally attributed to the agonist effects at 5-HT1D receptors.

The treatment is administered subcutaneously into the skin of the middle thigh and does not require refrigeration, assembly, or priming of the device.

No additional quotes available.

Author summary: Brekiya is now available for treating migraines and cluster headaches.

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Neurology Advisor Neurology Advisor — 2025-10-31